Hemogenyx Pharmaceuticals plc
(“Hemogenyx Pharmaceuticals” or the “Company”)
TR-1: Standard form for notification of major holdings
1. Issuer Details
ISIN
GB00BQVXM815
Issuer Name
HEMOGENYX PHARMACEUTICALS PLC
UK or Non-UK Issuer
UK
2. Reason for Notification
An acquisition or disposal of voting rights
3. Details of person subject to the notification obligation
Name
David John Smith
City of registered office (if applicable)
Grimsby
Country of registered office (if applicable)
United Kingdom
4. Details of the shareholder
| Name | City of registered office | Country of registered office |
| Transact Nominees Limited | London | England |
| Interactive Investor Services Nominees Limited | Manchester | England |
5. Date on which the threshold was crossed or reached
01-Sep-2025
6. Date on which Issuer notified
18-Sep-2025
7. Total positions of person(s) subject to the notification obligation
| . | % of voting rights attached to shares (total of 8.A) | % of voting rights through financial instruments (total of 8.B 1 + 8.B 2) | Total of both in % (8.A + 8.B) | Total number of voting rights held in issuer |
| Resulting situation on the date on which threshold was crossed or reached | 3.037600 | 0.000000 | 3.037600 | 143594 |
| Position of previous notification (if applicable) |
8. Notified details of the resulting situation on the date on which the threshold was crossed or reached
8A. Voting rights attached to shares
| Class/Type of shares ISIN code(if possible) | Number of direct voting rights (DTR5.1) | Number of indirect voting rights (DTR5.2.1) | % of direct voting rights (DTR5.1) | % of indirect voting rights (DTR5.2.1) |
| GB00BQVXM815 | 142898 | 696 | 3.022900 | 0.014700 |
| Sub Total 8.A | 143594 | 3.037600% | ||
8B1. Financial Instruments according to (DTR5.3.1R.(1) (a))
| Type of financial instrument | Expiration date | Exercise/conversion period | Number of voting rights that may be acquired if the instrument is exercised/converted | % of voting rights |
| Sub Total 8.B1 | ||||
8B2. Financial Instruments with similar economic effect according to (DTR5.3.1R.(1) (b))
| Type of financial instrument | Expiration date | Exercise/conversion period | Physical or cash settlement | Number of voting rights | % of voting rights |
| Sub Total 8.B2 | |||||
9. Information in relation to the person subject to the notification obligation
2. Full chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held starting with the ultimate controlling natural person or legal entities (please add additional rows as necessary)
| Ultimate controlling person | Name of controlled undertaking | % of voting rights if it equals or is higher than the notifiable threshold | % of voting rights through financial instruments if it equals or is higher than the notifiable threshold | Total of both if it equals or is higher than the notifiable threshold |
| David Smith | 3.037600 | 3.037600% | ||
| David Smith | GHC Property Services Limited | 0.014700 | 0.014700% |
10. In case of proxy voting
Name of the proxy holder
The number and % of voting rights held
The date until which the voting rights will be held
11. Additional Information
12. Date of Completion
13. Place Of Completion
Hull, England
TR-1: Standard form for notification of major holdings
1. Issuer Details
ISIN
GB00BQVXM815
Issuer Name
HEMOGENYX PHARMACEUTICALS PLC
UK or Non-UK Issuer
UK
2. Reason for Notification
An acquisition or disposal of voting rights
3. Details of person subject to the notification obligation
Name
David John Smith
City of registered office (if applicable)
Grimsby
Country of registered office (if applicable)
United Kingdom
4. Details of the shareholder
| Name | City of registered office | Country of registered office |
| GHC Property Services Limited | Grimsby | England |
| Copier Systems Limited | Scunthorpe | England |
| HBP Monpellier Limited | Carlisle | England |
| Kamarin Computers Limited | Scunthorpe | England |
| HBP Systems Limited | Scunthorpe | England |
| Transact Nominees Limited | London | England |
| Interactive Investor Services Nominees Limited | Manchester | England |
5. Date on which the threshold was crossed or reached
04-Sep-2025
6. Date on which Issuer notified
18-Sep-2025
7. Total positions of person(s) subject to the notification obligation
| . | % of voting rights attached to shares (total of 8.A) | % of voting rights through financial instruments (total of 8.B 1 + 8.B 2) | Total of both in % (8.A + 8.B) | Total number of voting rights held in issuer |
| Resulting situation on the date on which threshold was crossed or reached | 4.761400 | 0.000000 | 4.761400 | 240162 |
| Position of previous notification (if applicable) | 3.037600 | 0.000000 | 3.037600 |
8. Notified details of the resulting situation on the date on which the threshold was crossed or reached
8A. Voting rights attached to shares
| Class/Type of shares ISIN code(if possible) | Number of direct voting rights (DTR5.1) | Number of indirect voting rights (DTR5.2.1) | % of direct voting rights (DTR5.1) | % of indirect voting rights (DTR5.2.1) |
| GB00BQVXM815 | 170021 | 70141 | 3.370800 | 1.390600 |
| Sub Total 8.A | 240162 | 4.761400% | ||
8B1. Financial Instruments according to (DTR5.3.1R.(1) (a))
| Type of financial instrument | Expiration date | Exercise/conversion period | Number of voting rights that may be acquired if the instrument is exercised/converted | % of voting rights |
| Sub Total 8.B1 | ||||
8B2. Financial Instruments with similar economic effect according to (DTR5.3.1R.(1) (b))
| Type of financial instrument | Expiration date | Exercise/conversion period | Physical or cash settlement | Number of voting rights | % of voting rights |
| Sub Total 8.B2 | |||||
9. Information in relation to the person subject to the notification obligation
2. Full chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held starting with the ultimate controlling natural person or legal entities (please add additional rows as necessary)
| Ultimate controlling person | Name of controlled undertaking | % of voting rights if it equals or is higher than the notifiable threshold | % of voting rights through financial instruments if it equals or is higher than the notifiable threshold | Total of both if it equals or is higher than the notifiable threshold |
| David Smith | 4.761400 | 4.761400% | ||
| David Smith | GHC Property Services Limited | 0.289200 | 0.289200% | |
| David Smith | HBP Systems Limited | 0.275400 | 0.275400% | |
| David Smith | Kamarin Computers Limited | 0.275400 | 0.275400% | |
| David Smith | HBP Monpellier Limited | 0.275400 | 0.275400% | |
| David Smith | Copier Systems Limited | 0.275400 | 0.275400% |
10. In case of proxy voting
Name of the proxy holder
The number and % of voting rights held
The date until which the voting rights will be held
11. Additional Information
12. Date of Completion
13. Place Of Completion
Hull, England
TR-1: Standard form for notification of major holdings
1. Issuer Details
ISIN
GB00BQVXM815
Issuer Name
HEMOGENYX PHARMACEUTICALS PLC
UK or Non-UK Issuer
UK
2. Reason for Notification
An acquisition or disposal of voting rights
3. Details of person subject to the notification obligation
Name
David John Smith
City of registered office (if applicable)
Grimsby
Country of registered office (if applicable)
United Kingdom
4. Details of the shareholder
| Name | City of registered office | Country of registered office |
| GHC Property Services Limited | Grimsby | England |
| Copier Systems Limited | Scunthorpe | England |
| HBP Monpellier Limited | Carlisle | England |
| Kamarin Computers Limited | Scunthorpe | England |
| HBP Systems Limited | Scunthorpe | England |
| Transact Nominees Limited | London | England |
| Interactive Investor Services Nominees Limited | Manchester | England |
5. Date on which the threshold was crossed or reached
08-Sep-2025
6. Date on which Issuer notified
18-Sep-2025
7. Total positions of person(s) subject to the notification obligation
| . | % of voting rights attached to shares (total of 8.A) | % of voting rights through financial instruments (total of 8.B 1 + 8.B 2) | Total of both in % (8.A + 8.B) | Total number of voting rights held in issuer |
| Resulting situation on the date on which threshold was crossed or reached | 5.163200 | 0.000000 | 5.163200 | 260426 |
| Position of previous notification (if applicable) | 4.761400 | 0.000000 | 4.761400 |
8. Notified details of the resulting situation on the date on which the threshold was crossed or reached
8A. Voting rights attached to shares
| Class/Type of shares ISIN code(if possible) | Number of direct voting rights (DTR5.1) | Number of indirect voting rights (DTR5.2.1) | % of direct voting rights (DTR5.1) | % of indirect voting rights (DTR5.2.1) |
| GB00BQVXM815 | 190285 | 70141 | 3.772600 | 1.390600 |
| Sub Total 8.A | 260426 | 5.163200% | ||
8B1. Financial Instruments according to (DTR5.3.1R.(1) (a))
| Type of financial instrument | Expiration date | Exercise/conversion period | Number of voting rights that may be acquired if the instrument is exercised/converted | % of voting rights |
| Sub Total 8.B1 | ||||
8B2. Financial Instruments with similar economic effect according to (DTR5.3.1R.(1) (b))
| Type of financial instrument | Expiration date | Exercise/conversion period | Physical or cash settlement | Number of voting rights | % of voting rights |
| Sub Total 8.B2 | |||||
9. Information in relation to the person subject to the notification obligation
2. Full chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held starting with the ultimate controlling natural person or legal entities (please add additional rows as necessary)
| Ultimate controlling person | Name of controlled undertaking | % of voting rights if it equals or is higher than the notifiable threshold | % of voting rights through financial instruments if it equals or is higher than the notifiable threshold | Total of both if it equals or is higher than the notifiable threshold |
| David Smith | 5.163200 | 5.163200% | ||
| David Smith | GHC Property Services Limited | 0.289200 | 0.289200% | |
| David Smith | HBP Systems Limited | 0.275400 | 0.275400% | |
| David Smith | Kamarin Computers Limited | 0.275400 | 0.275400% | |
| David Smith | HBP Monpellier Limited | 0.275400 | 0.275400% | |
| David Smith | Copier Systems Limited | 0.275400 | 0.275400% |
10. In case of proxy voting
Name of the proxy holder
The number and % of voting rights held
The date until which the voting rights will be held
11. Additional Information
12. Date of Completion
13. Place Of Completion
Hull, England