TR-1: Standard form for notification of major holdings

1. Issuer Details

ISIN

GB00BQVXM815

Issuer Name

HEMOGENYX PHARMACEUTICALS PLC

UK or Non-UK Issuer

UK

2. Reason for Notification

An acquisition or disposal of voting rights

3. Details of person subject to the notification obligation

Name

David John Smith

City of registered office (if applicable)

Grimsby

Country of registered office (if applicable)

United Kingdom

4. Details of the shareholder

Name City of registered office Country of registered office
Interactive Investor Services Nominees LimitedManchesterEngland
Transact Nominees LimitedLondonEngland
HBP Systems LimitedScunthorpeEngland
Kamarin Computers LimitedScunthorpeEngland
HBP Monpellier LimitedCarlisleEngland
Copier Systems LimitedScunthorpeEngland
GHC Property Services LimitedGrimsbyEngland

5. Date on which the threshold was crossed or reached

06-Jan-2026

6. Date on which Issuer notified

09-Jan-2026

7. Total positions of person(s) subject to the notification obligation

.% of voting rights attached to shares (total of 8.A) % of voting rights through financial instruments (total of 8.B 1 + 8.B 2) Total of both in % (8.A + 8.B) Total number of voting rights held in issuer
Resulting situation on the date on which threshold was crossed or reached7.7620000.0000007.762000468923
Position of previous notification (if applicable)6.7506400.0000006.750640

8. Notified details of the resulting situation on the date on which the threshold was crossed or reached

8A. Voting rights attached to shares

Class/Type of shares ISIN code(if possible) Number of direct voting rights (DTR5.1) Number of indirect voting rights (DTR5.2.1) % of direct voting rights (DTR5.1) % of indirect voting rights (DTR5.2.1)
GB00BQVXM8152119762569473.5088004.253200
Sub Total 8.A4689237.762000%

8B1. Financial Instruments according to (DTR5.3.1R.(1) (a))

Type of financial instrument Expiration date Exercise/conversion period Number of voting rights that may be acquired if the instrument is exercised/converted % of voting rights
Sub Total 8.B1

8B2. Financial Instruments with similar economic effect according to (DTR5.3.1R.(1) (b))

Type of financial instrument Expiration date Exercise/conversion period Physical or cash settlement Number of voting rights % of voting rights
Sub Total 8.B2

9. Information in relation to the person subject to the notification obligation

2. Full chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held starting with the ultimate controlling natural person or legal entities (please add additional rows as necessary)

Ultimate controlling person Name of controlled undertaking % of voting rights if it equals or is higher than the notifiable threshold % of voting rights through financial instruments if it equals or is higher than the notifiable threshold Total of both if it equals or is higher than the notifiable threshold
David Smith7.7620007.762000%
David SmithGHC Property Services Limited2.4140002.414000%
David SmithHBP Systems Limited0.4598000.459800%
David SmithKamarin Computers Limited0.4598000.459800%
David SmithHBP Monpellier Limited0.4598000.459800%
David SmithCopier Systems Limited0.4598000.459800%

10. In case of proxy voting

Name of the proxy holder

The number and % of voting rights held

The date until which the voting rights will be held

11. Additional Information

12. Date of Completion

09-Jan-2026

13. Place Of Completion

Hull, England